PUPTIDE
Active ingredients per 1 mL (one full dropper): beta-nicotinamide mononucleotide (NMN) 60 mg; USP-grade methylene blue, purity 99% or higher.
Inactive: vegetable glycerin, purified water. No proprietary blend, no filler botanicals, no sweetener.
Never included: xylitol, alcohol, grain, artificial flavour or colour.
Dosed by body weight: 0.5 ml for dogs under 25 lbs, 1 ml for 25 to 60 lbs, 1.5 ml for over 60 lbs.
Shake well, then squeeze the dose onto food or give it directly onto the tongue. Daily, ideally with a meal.
Methylene blue is a pharmaceutical-grade compound with over a century of medical use. At low doses it acts as a cellular antioxidant and supports the mitochondria's ability to produce energy efficiently, the same pathway NMN works on from a different angle.
Beyond the mitochondrial support, it has antimicrobial effects and works as a natural urinary antiseptic, giving it a second role in the formula.
We use USP-grade, triple-tested material at a low, dog-appropriate level.
Talk to your vet before starting, particularly if your dog is on medication or managing a health condition. Canine-specific data on NMN is thinner than the human literature, and we'd rather say that plainly.
Methylene blue specifically: if your dog is on an SSRI, MAOI, or other serotonergic medication, check with your vet first. That combination is the one interaction worth ruling out before you start.
Not for puppies, or for pregnant or nursing dogs. Formulated and dosed for dogs, not cats.
Every batch is assayed for NMN content and methylene blue purity, and screened for lead, arsenic, cadmium and mercury. Certificates are available by lot number.
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Benefits of Puptide Blend for Dogs
Dogs can't describe low energy, slower mornings, or a sluggish afternoon. Puptide is designed to support the cellular energy pathway before those changes show.
Feeding instructions
Puptide is simple to use, easy to absorb, and dosed by body weight for all breeds and life stages.
Shake the bottle well. Squeeze the dose onto your dog's food and mix it in. Repeat daily, ideally with a meal.
Shake the bottle well. Using the dropper, give the dose directly onto your dog's tongue. Repeat daily for best results.
Two actives. Printed, not implied.
Independent testing has found most top-selling pet NMN products miss their own label claim. Here is everything in ours, with nothing else to disclose.
NMN is a small molecule the body converts into NAD+, a coenzyme every cell needs to turn food into usable energy. NAD+ itself is too large to cross into cells efficiently when given orally, which is why the precursor is the ingredient that actually does the work.
It's the most direct oral route to raising NAD+ availability, and canine safety data exists at the doses used here. A beagle toxicity study found only mild, dose-dependent changes at levels far above what's in a daily dropper.
Methylene blue is a pharmaceutical-grade compound used in medicine for over a century. It acts as a cellular antioxidant and mitochondrial enhancer, helping cells produce energy more efficiently, and is known for neuroprotective properties at low doses. We use USP-grade, triple-tested methylene blue.
It supports energy, antioxidant balance, and longevity at the cellular level, and was chosen for its safety profile in dogs at low doses. It pairs with the NMN to work the same mitochondrial pathway from a second angle without overstimulating anything.
Vegetable glycerin and purified water. That's the entire carrier, and it's the entire rest of the formula.
Nothing in the bottle that isn't doing a job or carrying something that is. A short ingredient list is easier to verify, easier to print in full, and easier for you to check against the certificate.
What you're actually comparing
Measured against typical pet supplement label practices, not any specific brand.
Compared against common formats and label practices in the category.
What owners are reporting
Common questions about Puptide
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Start with one bottle
One squeeze on dinner, dosed to his weight. If it isn't for him, the 60-day guarantee covers it.
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